Method for early detection of infectious mononucleosis by identi

Details Method for early detection of infectious mononucleosis by identi Method for early detection of infectious mononucleosis by identi

1982-08-10

1984-10-02

Marantz, Sidney

Chemistry: analytical and immunological testing

Biological cellular material tested

204180G, 204403, 260112R, 436 56, 436 86, 436812, G01N 3368, G01N 3350, G01N 2726

Patent

active

044748868

ABSTRACT:
Early detection of infectious mononucleosis is carried out using a sample of human blood by isolating and identifying the presence of Inmono proteins in the sample from a two-dimensional protein map with the proteins being characterized by having isoelectric banding as measured in urea of about -16 to -17 with respect to certain isoelectric point standards and molecular mass of about 70 to 75 K daltons as measured in the presence of sodium dodecylsulfate containing polyacrylamide gels, the presence of the Inmono proteins being correlated with the existence of infectious mononucleosis.

REFERENCES:
patent: 4244803 (1981-01-01), Aladjem
patent: 4301142 (1981-11-01), Enders
patent: 4322274 (1982-03-01), Wilson
MacKinney, Jr., Archie A., Blood, vol. 32(2), 217-224 (1968).
Willard, Karen E., Clin. Chem., vol. 28(4), 1031-1035 (1982).
Edwards, Jesse J. et al., Clin. Chem., vol. 28(1), 160-163 (1982).

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