Method for distributing a pharmaceutically active compound...

Details Method for distributing a pharmaceutically active compound... Method for distributing a pharmaceutically active compound...

2011-07-12

2011-07-12

Hartley, Michael G (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S464000, C424S465000

Reexamination Certificate

active

07976872

ABSTRACT:
A process for uniformly distributing a pharmaceutically active particulate material in a pharmaceutically inert particulate material includes steps of providing a first layer of a pharmaceutically inert particulate material, disposing a layer of a pharmaceutically active particulate material on the first layer of pharmaceutically inert particulate material, passing the layers of particulate material through a static mixer, and discharging the blended mixture from the static mixer. The process is particularly useful for blending a low dose, high potency drug having a propensity to stick to process equipment surfaces with pharmaceutically inert particulate materials, such as diluents and/or excipients.

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