Method for distinguishing viable, early apoptotic, late apoptoti

Details Method for distinguishing viable, early apoptotic, late apoptoti Method for distinguishing viable, early apoptotic, late apoptoti

1997-11-10

1999-08-31

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 78, 436501, 436548, 436800, 5303871, 5303881, G01N 3353

Patent

active

059452919

ABSTRACT:
The present invention provides a method for distinguishing between viable, early apoptotic, late apoptotic and necrotic cells utilizing multi-color immunofluorescence.

REFERENCES:
Vermes et al (1995) Journal of Immunological Methods vol. 184 No. 1 pp. 39-51.
J. Ameisen et al, Immunol. Today, 12:102-105 (1991).
J. Kerr et al, Br. J. Cancer, 26:239 (1972).
A. Wyllie, Nature, 284:555 (1980).
C. Zhang et al, J. Immunol., 157:3980-3987 (1996).
I. Schmid et al, Cytometry, 15:12-20 (1994).
O'Brien et al, Cytometry, 28:81-89 (1997).

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