Method for distinguishing subpopulations in a population of morp

Details Method for distinguishing subpopulations in a population of morp Method for distinguishing subpopulations in a population of morp

1976-08-30

1978-01-24

Tanenholtz, Alvin E.

Textiles: fiber preparation

195 99, 195101, 1951035R, 195112, C12K 102, C12K 900

Patent

active

040702430

ABSTRACT:
A method for identification of cell subpopulations in a population of cells which are morphologically alike, based on the ability of selected strains of bacteria to bind to the cell surface when they are brought in close contact.
Selected strains of naturally occurring or artificially obtained bacteria of different species or genuses, having an affinity to bind to different subpopulations of a cell mixture, are brought into contact by centrifugation or the like with a mixture of cells such as leukocytes, the mixture is resuspended and the cells having bacteria attached are identified under the microscope. The method is useful particularly for the identification of B cells, several subpopulations of T cells, and the differentiation among leukemic cell populations.

REFERENCES:
ghetie et al., Eur. J. Immunol. vol. 4 (1974) pp. 500-505.

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