Method for distinguishing alcoholics from non-alcoholics

Details Method for distinguishing alcoholics from non-alcoholics Method for distinguishing alcoholics from non-alcoholics

1988-12-21

1991-11-19

Saunders, David A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 19, 435 29, 436 63, 436 71, 436162, 436901, C12Q 102, C12Q 134, C12Q 144

Patent

active

050665839

ABSTRACT:
A method for distinguishing an alcoholic person from non-alocholic persons which comprises measuring the potential of lymphocytes from that person to produce phosphatidylenthanol and comparing the results obtained with a standard obtained from the lymphocytes of persons which are known not to be at substantial risk of becoming alcohol dependent which lymphocytes were incubated under identical conditions.

REFERENCES:
patent: 4770996 (1988-09-01), Tasakoff
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Kinsky et al., Biochem. Biophys. Res. Communic. 162, 788-793, 1989.
Diamond et al., Proc. Natl. Acad. Sci. USA, 84, 1413-1416, 1987.
Mueller et al., Proc. Natl. Acad. Sci. USA, 85, 9778-9782, 1988.
Wrighton, S. A., Pai, J. K. and Mueller, G. C. (1983) Carcinogenesis 4, 1247-1251.
Pai, J. K., Liebl, E. C., Tettenborn, C. S., Ikegwunonu, F. I. and Mueller, G. C. (1987) Carcinogenesis 8, 173-178.
Tettenborn, C. S. and Mueller, G. C. (1987) Biochem. Biophys. Acta 931, 242-250.
Pai, J. K., Siegel, M. I., Egan, R. W. and Billah, M. M. (1988) Biochem. Biophys. Res. Commun. 150, 355-364.
Tettenborn, C. S. and Mueller, G. C. (1988) Biochem. Biophys. Res. Commun., vol. 155, No. 1.
Alling, C., Gustavsson, L. and Anggard, E. (1983) FEBS Lett. 152, 24-28.

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