Measuring and testing – Sampler – sample handling – etc. – Capture device
Patent
1999-04-30
2000-09-05
Noland, Thomas P.
Measuring and testing
Sampler, sample handling, etc.
Capture device
422930, B67D 508, B01L 302, G01F 2500
Patent
active
061126055
ABSTRACT:
A low volume liquid handling system is described which includes a microdispenser employing a piezoelectric transducer attached to a glass capillary, a positive displacement pump for priming and aspirating liquid into the microdispenser, controlling the pressure of the liquid system, and washing the microdispenser between liquid transfers, and a pressure sensor to measure the liquid system pressure and produce a corresponding electrical signal. The pressure signal is used to verify and quantify the microvolume dispensed and is used to perform automated calibration and diagnostics on the microdispenser.
REFERENCES:
patent: 3427480 (1969-02-01), Robinson
patent: 3452360 (1969-06-01), Williamson
patent: 3507269 (1970-04-01), Berry
patent: 3512173 (1970-05-01), Darmouth
patent: 3549328 (1970-12-01), Kilburn
patent: 3666421 (1972-05-01), Price
patent: 3683212 (1972-08-01), Zoltan
patent: 3711252 (1973-01-01), Roy
patent: 3831845 (1974-08-01), Packt
patent: 3832579 (1974-08-01), Arndt
patent: 3838012 (1974-09-01), Higgens
patent: 3859169 (1975-01-01), O'Driscoll et al.
patent: 3902083 (1975-08-01), Zoltan
patent: 3933439 (1976-01-01), McDonald
patent: 3946398 (1976-03-01), Kyser et al.
patent: 3958249 (1976-05-01), DeMaine et al.
patent: 3964871 (1976-06-01), Hochstrasser
patent: 3975162 (1976-08-01), Renn
patent: 3985467 (1976-10-01), Lefferson
patent: 3994423 (1976-11-01), Burg
patent: 3996006 (1976-12-01), Pagano
patent: 4038570 (1977-07-01), Durley, III
patent: 4046513 (1977-09-01), Johnson
patent: 4084165 (1978-04-01), Skafvensted et al.
patent: 4087332 (1978-05-01), Hansen
patent: 4130394 (1978-12-01), Negersmith
patent: 4193009 (1980-03-01), Durley, III
patent: 4216245 (1980-08-01), Johnson
patent: 4234103 (1980-11-01), Strobl, Jr. et al.
patent: 4241406 (1980-12-01), Kennedy et al.
patent: 4278983 (1981-07-01), Halasz
patent: 4293867 (1981-10-01), Isayama
patent: 4298575 (1981-11-01), Bergland
patent: 4308546 (1981-12-01), Halasz
patent: 4341310 (1982-07-01), Sangiovanni et al.
patent: 4366490 (1982-12-01), DeBonte et al.
patent: 4418356 (1983-11-01), Reece
patent: 4426031 (1984-01-01), Halasz
patent: 4447375 (1984-05-01), Schimmelpfennig
patent: 4459267 (1984-07-01), Bunce et al.
patent: 4476999 (1984-10-01), Bilbrey
patent: 4492322 (1985-01-01), Hieftje et al.
patent: 4498088 (1985-02-01), Kanayama
patent: 4503012 (1985-03-01), Starr
patent: 4504845 (1985-03-01), Kattner et al.
patent: 4512722 (1985-04-01), Mouton
patent: 4514743 (1985-04-01), Roschlein et al.
patent: 4518974 (1985-05-01), Isayama
patent: 4530463 (1985-07-01), Hiniker et al.
patent: 4539575 (1985-09-01), Nilsson
patent: 4548825 (1985-10-01), Voss et al.
patent: 4550325 (1985-10-01), Viola
patent: 4600928 (1986-07-01), Braun et al.
patent: 4646104 (1987-02-01), Braun
patent: 4651161 (1987-03-01), Rich et al.
patent: 4672398 (1987-06-01), Kuwabara et al.
patent: 4681741 (1987-07-01), Hanaway
patent: 4682710 (1987-07-01), Turner, Jr. et al.
patent: 4695852 (1987-09-01), Scardovi
patent: 4701754 (1987-10-01), Provonchee
patent: 4780783 (1988-10-01), Atake
patent: 4877745 (1989-10-01), Hayes et al.
patent: 4976259 (1990-12-01), Higson et al.
patent: 5053100 (1991-10-01), Hayes et al.
patent: 5055263 (1991-10-01), Meltzer
patent: 5059393 (1991-10-01), Quenin et al.
patent: 5072235 (1991-12-01), Slowik et al.
patent: 5141871 (1992-08-01), Kureshy et al.
patent: 5158748 (1992-10-01), Obi et al.
patent: 5225750 (1993-07-01), Higuchi et al.
patent: 5232664 (1993-08-01), Krawzak et al.
patent: 5297734 (1994-03-01), Toda
patent: 5306510 (1994-04-01), Meltzer
patent: 5334353 (1994-08-01), Blattner
patent: 5356034 (1994-10-01), Schlumberger
patent: 5365783 (1994-11-01), Zweitel
patent: 5457527 (1995-10-01), Manns et al.
patent: 5485828 (1996-01-01), Hauser
patent: 5488854 (1996-02-01), Kawanabe et al.
patent: 5529754 (1996-06-01), Bonacina et al.
patent: 5630793 (1997-05-01), Rowe
patent: 5693016 (1997-12-01), Gumaste et al.
patent: 5920829 (1999-07-01), Bretmersky et al.
patent: 5927547 (1999-07-01), Papen et al.
BioTechniques; A. Schober et al; Product Application Focus "Accurate High-Speed Liquid Handling of Very Small Biological Samples" 1993 Month not Given, vol. 15, No. 2, pp. 324-329.
Abstracts of JP 7-120472A by JPO & Derwent Information Ltd & Image by GPIC, Derwent Abstract Acs Acc No. 1995-209664 Derwent Week 1995 28 JP 7-120412A dated May 12, 1995.
Boillat et al., "A Differential Pressure Liquid Flow Sensor for Flow Regulation and Dosing Systems," Proceedings IEEE, Micro Electro Mechanical Systems, MEMS, '95 Amsterdam.
Schober, A., et al., "Accurate High-Speed Liquid Handling of Very Small Biological Samples," BioTechniques, vol. 15, No. 2 (1993), p, 324-329.
Plunkett, Matthew J. et al., "Combinatorial Chemistry and New Drugs," Scientific American, Apr. 1997, p. 69-73.
Microdrop Instruction Manual, Microdrop Gesellschaft fur Mikrodosiersysteme mbH, MD-K-130SP/140H/135/150 and Drive electronics MD-E-204, May 1994.
Microdrop Instruction Manual, Microdrop Gesellschaft fur Mikrodosiersysteme mbH, AD-E-130, Sep. 1995.
"Microdosing in the picoliter range with piezo technology" sales brochure from Microdrop Gesellschaft fur Mickrodosiersysteme mbH, Oct., 1995.
Joshi and Sacks, "Circular Slot Burner-Droplet Generator System for High-Temperature Reaction and Vapor Transport Studies", pp. 1781-1785, Analytical Chemistry, vol. 51, No. 11, Sep. 1979.
Holcombe, Eklund & Grice, "Vaporization and Atomization of Large Particles in an Acetylene/Air Flame", pp. 2097-2103, Analytical Chemistry, vol. 50, No. 14, Dec. 1978.
Buehner, et al., "Application of Ink Jet Technology to a Word Processing Output Printer", pp. 1-9, IBM J. Res. Develop.
Curry, Portig, "Scale Model of an Ink Jet", pp. 10-20, IBM J. Res. Develop.
Pimbley "Satellite Droplet Formation in a Liquid Jet" pp. 21-30, Satellite Formation, IBM J. Res. Develop.
Twardeck "Effect of Parameter Variations on Drop Placement in an Electrostatic Ink Jet Printer" pp. 31-36, IBM J. Res. Develop.
Filmore et al. Drop Charging and Deflection in an Electrostatic Ink Jet Printer, pp. 37-47, IBM J. Res. Develop.
Lee "Boundary Layer Around a Liquid Jet" pp. 48-51, IBM J. Res. Develop.
Carmichael, "Controlling Print Height in an Ink Jet Printer" pp. 52-55, IBM J. Res. Develop.
Levanoni, "Study of Fluid Flow through Scaled-up Ink Jet Nozzles" pp. 56-68, IBM J. Res. Develop.
Ashley et al. "Development and Characterization of Ink for an Electrostatic Ink Jet Printer" pp. 69-74, IBM J. Res. Develop.
Beach et al., "Materials Selection for an Ink Jet Printer" pp. 75-86, IBM J. Res. Develop.
Chibucos Nicholas S.
Meyer Wilhelm
Papen Roeland F.
Pelc Richard E.
Noland Thomas P.
Packard Instrument Company
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