Method for disinfecting immobilized enzymes

Details Method for disinfecting immobilized enzymes Method for disinfecting immobilized enzymes

1980-11-12

1983-07-12

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an...

426 41, 4263302, 426335, 435174, 435207, 435234, C12N 1114, C12N 1100, C12N 938, C12N 992

Patent

active

043931383

ABSTRACT:
Disinfecting of immobilized enzymes is carried out by contacting the immobilized enzymes with a dilute aqueous solution of at least one substituted diethylenetriamine at a concentration and for a period of time which is sufficient to substantially kill the contaminating microorganisms without significant deleterious effects on the immobilized enzymes. The substituted diethylenetriamine is preferably dioctyldiethylenetriamine or a mixture of dioctyldiethylenetriamine and trioctyldiethylenetriamine.

REFERENCES:
patent: 4229536 (1980-10-01), DeFilippi
Pitcher et al., Development of An Adsorbed Lactase Immobilized Enzyme System, Enzyme Engineering, vol. 3, Plenum Publishing Corp., 1978, (pp. 483-496).
Weetall, et al., Preparation of Immobilized Lactase, Biotechnol. and Bioeng., vol. XVI, 1974 (pp. 689-696).

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