Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1984-06-18
1986-05-13
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424130, 435 78, 435264, 514902, A61K 3748, A61K 3340, C12P 1956, D06M 1600
Patent
active
045885869
ABSTRACT:
The method comprises forming a bactericide having a limited period of bacteriological activity with the bactericide comprising three components including a peroxide, a peroxidase and a source of donor molecules adopted to act as a substrate for the peroxidase; storing the three components in a nonreacting state to maintain the bactericide inactive and admixing the three components in a liquid carrier to cause a catalyzed reaction by said peroxidase for generating free radicals from the source of donor molecules and immersing the contact lens into the solution simultaneously with the admixture. The concentration level of the three components should be selected such that a substantial portion of the peroxide is consumed during the catalyzed reaction.
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Sizer, I. W.-The Oxidative Inactivation of Poison Ivy Allergens by Peroxidase: J. Invest. Dermatology, 16, 103-110 (1951).
Wennstrom et al.-Effect of Hydrogen Peroxide on Developing Plaque and Gingivitis in Man: J. Clinical Period., 6, 115-130 (1979).
Kessler Jack H.
Rosenbaum Robert S.
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