Method for differentiation of Alzheimer's Disease into...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Reexamination Certificate

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10890508

ABSTRACT:
A method for diagnosing distinct subgroups of Alzheimer's Disease, the method comprising the steps of obtaining a sample of cerebrospinal fluid and determining the level of ubiquitin, the level of Aβ1-42, and the level of tau present in the sample. Based on the levels of each composition in the cerebrospinal fluid, the sample can be assigned to distinct subgroups.

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Hu 2002. American Journal of Pathology 160:1269-1278.
Iqbal 2002. Tatl tau, A beta (1-42) and ubiquitin in CSF in the diagnosis of Alzheimer disease European Psychiatry 17(1):p. 76S.

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