Method for differentiating mesenchymal stem cell into neural...

Details Method for differentiating mesenchymal stem cell into neural... Method for differentiating mesenchymal stem cell into neural...

2003-10-29

2009-12-22

Sajjadi, Fereydoun G (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C435S325000, C435S372000

Reexamination Certificate

active

07635591

ABSTRACT:
The present invention provides a method of differentiating and proliferating a mesenchymal stem cell into the neural cell by culturing in a medium comprising an epidermal growth factor and a hepatocyte growth factor after confluent culture of the mesenchymal stem cell. The present invention provides more effective method of differentiating and proliferating the mesenchymal stem cell or the mononuclear cell comprising the mesenchymal stem cell into the neural cell with a neuron and an astrocyte in terms of time, efficiency and maturity as compared with conventional methods.

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Sanchez-Ramos et al.; “Adult Bone Marrow Stromal Cells Differentiate into Neural Cells in Vitro”; Experimental Neurology; 2000; vol. 164; pp. 247-250.

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