Method for differential diagnosis of meningitis with a limulus l

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195127, C12K 104

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040677761

ABSTRACT:
A method for rapid bedside diagnostic differentiation between aseptic meningitis and Gram-negative bacterial meningitis is carried out in a positive control vessel, a negative control vessel and a test vessel, wherein each vessel contains an equal amount of lyophilized limulus lysate and the positive control vessel also contains an amount of lyophilized Gram-negative bacterial endotoxin.

REFERENCES:
patent: 3704206 (1972-11-01), Freake et al.
patent: 3876503 (1975-04-01), Mennen
patent: 3893892 (1975-07-01), Mehl
patent: 3954663 (1976-05-01), Yamamoto et al.
Nachum et al "Rapid Detection of Gram-Negative Bacterial Meningitis by the Limulus Lysate Test" The New England J. of Med., vol. 289, (1973) pp. 931-934.
Stumacher et al "Limitations of the Usefulness of the Limulus Assay for Endotoxin" New England J. of Med., vol. 288, (1973) pp. 1261-1264.
Worthington's World, vol. 3, No. 2, (1975) Published by Worthington Biochemical Corporation, Freehold, N. J. 07728.

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