Method for diagnosis and treating cancers, and methods for ident

Semiconductor device manufacturing: process – Including control responsive to sensed condition – Optical characteristic sensed

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435 6, 436 64, 436813, G01N 33574, C12Q 168

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active

058887512

ABSTRACT:
The invention involves the recognition of a previously identified protein, SCP-1, as a marker for cell transformation. Diagnostic and therapeutic uses of this protein and related molecules are taught. Also disclosed is a method for identifying substances which are immunoreactive and indicative of pathological conditions, using normal cells as source material.

REFERENCES:
Tureci et al., PNAS, vol. 95, No. 9, pp. 5211-5216, Apr. 28, 1998.
Heyting et al., "Synaptonemal Complex Proteins", Genome 31: 81-87 (1989).
Meuwissen et al., "A coiled coil related protein specific for synapsed regions of meiotic prophase chromosome", EMBO J 11 (13:5091-5100 (1992).
Sage et al., cDNA sequence of the murine synaptonemal complex protein 1 (SCP1) Biochimica Biophipica Acta 1263: 258-260 (1995).
Meuwissen et al., "Human Synaptonemal Complex Protein 1 (SCP1) : Isolation and Characterization of the cDNA and Chromosomal Localization of the Gene", Genomics 39: 377-384 (1996).

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