Method for diagnosing tumors using mouse monoclonal antibodies

Details Method for diagnosing tumors using mouse monoclonal antibodies Method for diagnosing tumors using mouse monoclonal antibodies

1994-12-22

1997-03-18

Adams, Donald E.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds eukaryotic cell or component thereof or substance...

4241301, 4241721, 4241791, 4241781, 424 149, 5303871, 5303888, 5303913, A61K 39395, A61K 5110, C07K 1600, C07K 1628

Patent

active

056120320

ABSTRACT:
The subject invention relates to monoclonal antibodies and uses thereof. In particular, the invention relates to three monoclonal antibodies, referred to as B1, B3, and B5, which are useful in the treatment and diagnosis of many forms of cancer.

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Abe et al., J. Biol. Chem., 258(19):11793-11797 (1983).
Bast et al., J. Clin. Invest., 68:1331-1337 (1991).
Fine et al., J. Invest. Dermatol., 92(16):825-830 (1989).
Hamilton et al., Cancer Res., 43:5379-5389 (1983).
Hellstrom et al., Cancer Res., 50:2183-22190 (1990).
Osborne et al., J. Invest. Dermatol., 85:385-388 (1985).
Pastan et al., Cell, 47:641-648 (1986).
Pastan et al., Cancer Res., 51:3781-3787 (1991).

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