Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reissue Patent
2007-05-09
2009-11-24
Yaen, Christopher H (Department: 1643)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
Reissue Patent
active
RE041007
ABSTRACT:
A method for the early diagnosing of selected adenocarcinomas in a human comprising the steps of removing a bodily sample from the human, and assaying the bodily sample for elevated expression of a specific gene. The gene being assayed for in thedelete-start id="DEL-S-00001" date="20091124" ?,delete-end id="DEL-S-00001" ?bodily sample is the TGFB-4 gene (hereinafter referred to as the endometrial bleeding associated factor (ebaf) gene. The bodily sample can be tissue from a specific organ in the body, or a blood sample. Increased levels of ebaf in the sample relative to basal levels may be indicative of a mucinous adenocarcinoma of the colon or ovaries, or an adenocarcinoma of the testis.
REFERENCES:
patent: 4444879 (1984-04-01), Foster et al.
patent: 5286624 (1994-02-01), Terashima et al.
patent: 5395825 (1995-03-01), Feinberg et al.
patent: 5420016 (1995-05-01), Boguslaski et al.
patent: 5554339 (1996-09-01), Cozzette et al.
patent: 5616561 (1997-04-01), Barcellos-Hoff
patent: 5693479 (1997-12-01), Feinberg et al.
patent: 5709837 (1998-01-01), Mori et al.
patent: 5874479 (1999-02-01), Martin
patent: 5916751 (1999-06-01), Tabibzadeh et al.
patent: 6027917 (2000-02-01), Celeste et al.
patent: 6040431 (2000-03-01), Keck et al.
patent: 6242568 (2001-06-01), Barbas et al.
patent: 6294662 (2001-09-01), Tabibzadeh
patent: 6428966 (2002-08-01), Lee et al.
patent: 6492497 (2002-12-01), Thompson et al.
patent: 6635480 (2003-10-01), Lee et al.
patent: 6649588 (2003-11-01), Tabibzadeh et al.
patent: 6677432 (2004-01-01), Oppermann et al.
patent: 6683156 (2004-01-01), Tabibzadeh
patent: 6747004 (2004-06-01), Tabibzadeh
patent: 7211644 (2007-05-01), Tabibzadeh
patent: 2003/0022841 (2003-01-01), Lee et al.
patent: 2003/0032047 (2003-02-01), Tabibzadeh
patent: 2003/0064069 (2003-04-01), Thompson et al.
patent: 2003/0091566 (2003-05-01), Thompson et al.
patent: 2005/0276802 (2005-12-01), Adams et al.
patent: 2007/0172870 (2007-07-01), Tabibzadeh
patent: 2008/0200379 (2008-08-01), Tabibzadeh
patent: WO 99/06443 (1999-02-01), None
patent: WO 99/06444 (1999-02-01), None
patent: WO 99/55902 (1999-11-01), None
patent: WO 01/01134 (2001-01-01), None
U.S. Appl. No. 11/801,427, filed May 9, 2007, Tabibzadeh.
RNA Image Kit Product Brochure, 1993, pp. 1-21.
“DNA Sequencing by the Dideoxy Method,” Sequences Ver. 2.0 A New Genetically Engineered Enzyme for DNA Sequencing, U.S. Biochemical Corp., 1988-89, pp. 7-29-7-35.
Analysis of RNA by Northern and Slot Blot Hybridization, Current Protocols in Molecular Biology, Unit 4.9, 1993, pp. 4.9.1-4.9.14.
Hillier et al. Genbank Accession No. R37562, May 1995.
Frigerio et al. Genbank Accession No. T25016, May 1995.
Liang et al. “Differential Display Using One-Base Anchored Oligo-dT Primers”Nucleic Acids Research, 1994, pp. 5763-5764, vol. 22, No. 25.
Tabibzadeh et al. “Distinct Tumor Specific Expression of TGFB4 (ebaf), a Novel Human Gene of the TGF-B Superfamily”Frontiers in Bioscience 2, Jul. 1997, pp. 18-25.
Tabibzadeh et al. “Dysregulated Expression of ebaf, a Novel Molecular Defect in the Endometria of Patients with Infertility”The Journal of Clinical Endocrinology&Metabolism, Mar. 8, 2000, pp. 2526-2536, vol. 85, No. 7.
Tabibzadeh et al. “Temporal and Site-Specific Expression of Transforming Growth Factor-β4 in Human Endometrium”Molecular Human Reproduction, 1998, pp. 595-602, vol. 4, No. 6.
“Radioimmunoassay”, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/Radioimmunoassay.html, Mar. 2005, pp. 1-3.
Capecchi, M.R., “Altering the Genome by Homologous Recombination”Science, 1989, pp. 1288-1292, vol. 244, No. 4910.
Davies, N.P., et al. “Targeted alterations in yeast artificial chromosomes for inter-species gene transfer”Nucleic Acids Research, 1992, pp. 2693-2698, vol. 20, No. 11.
Huxley, C., et al. “The Human HPRT Gene on a Yeast Artificial Chromosome is Functional When Transferred to Mouse Cells by Cell Fusion”Genomics, 1991, pp. 742-750, vol. 9.
Jakobovits, A., et al., “Germ-line transmission and expression of a human-derived yeast artificial chromosome ”Nature, Mar. 18, 1993, pp. 255-261, vol. 362.
Johnson, S. and Bird, R.E., “Construction of Single-Chain Fv Derivatives of Monoclonal Antibodies and Their Production inEscherichia coli”Methods in Enzymology, 1991, pp. 88-99, vol. 203, JJ Langone ed,; Academic Press, New York, NY.
Lamb, B.T., et al., “Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice”Nature Genetics, Sep. 1993, pp. 22-29, vol. 5.
Pearson, B.E. and Choi, T.K., “Expression of the human β-amyloid precursor protein gene from a yeast artificial chromosome in transgenic mice”Proceedings of the National Academy of Sciences USA, Nov. 1993, pp. 10578-10582, vol. 90.
Rothstein, R., “Targeting, Disruption, Replacement, and Allele Rescue: Integrative DNA Transformation in Yeast”Methods in Enzymology1991, pp. 281-301, vol. 194, Chapter 19, Guide to Yeast Genetics and Molecular Biology, eds. C. Guthrie and G. Fink, Academic Press, Inc.
Schedl, A., et al., “A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice”Nature, Mar. 18, 1993, pp. 258-261, vol. 362.
Strauss, W.M., et al., “Germ Line Transmission of a Yeast Artificial Chromosome Spanning the Murine a1(l) Collagen Locus”Science, Mar. 26, 1993, pp. 1904-1907, vol. 259, No. 5103.
Gruidl, M., et al., “The progressive rise in the expression of α crystalline B chain in human endometrium is initiated during the implantation window: modulation of gene expression by steroid hormones”Molecular Human Reproduction, 1997, pp. 333-342, vol. 3, No. 4.
Lessey, B.A., et al., “Integrin Adhesion Molecules in the Human Endometrium, Correlation with the Normal and Abnormal Menstrual Cycle”The Journal of Clinical Investigation, Jul. 1992, pp. 188-195, Vo. 90.
Kumar, S., et al., “Progesterone Induces Calcitonin Gene Expression in Human Endomentrium within the Putative Window of Implantation”Journal of Clinical Endocrinology and Metabolism, 1998, pp. 4443-4450, vol. 83, No. 12.
Molloy, S.S., et al., “Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis”Trends in Cell Biology, Jan. 1999, pp. 28-35, vol. 9.
Kothapalli, Ravi et al. “Detection of ebaf, a Novel Human Gene of the Transforming Growth Factor B Superfamily”,Journal of Clinical Investigation, May 1997, pp. 2342-2350, vol. 99, No. 10.
Leonard, S.N., et al., “Transforming growth factor beta 1 expression in the endometrium of the mare during placentation”Molecular Reproduction and Development, 1995, pp. 131-140, vol. 42.
Wieczorek, Z., et al., “The immunomodulatory diversity of the proteins of the transforming growth B (TGFB) family”International Journal of Peptide and Protein Research, Jul. 1995, pp. 113-118, vol. 46.
Meno, Chikara, et al., “Left-right asymmetric expression of the TGFB-family member lefty in mouse embryos”Nature, May 9, 1996, vol. 381.
Burt, D.W., et al., “Multiple growth factor mRNAs are expressed in chicken adipocyte precursor cells”Biochemical and Biophysical Research Communications, Sep. 30, 1992, pp. 1298-1305, vol. 187, No. 3.
Bowie, James U., et al., “Deciphering the Message in Protein Sequences: Tolerance to amino acid substitution”Science, Mar. 16, 1990, pp. 1306-1310, vol. 247.
Bassi et al., Accession Nos. AF081508; AF081510; AF081509, Jun. 23, 2006, p. 1.
Meno, et al., “Left-right asymmetric expression of the TFGβ-family member lefty in mouse embryos”Nature1996, reference of record, 151-155.
Sporn, M.B., et al., “TFGβ: problems and prospects”,Cell Regulation, The American Society of Cell Biology, Nov. 1990, pp. 875-882.
Roberts, A.B., et al., “Transformin
Kothapalli Ravi
Tabibzadeh Siamak
Saliwanchik Lloyd & Saliwanchik
University of South Florida
Yaen Christopher H
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