Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1979-04-04
1982-02-09
Kyle, Deborah L.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
23230B, 424 12, G01N 3348
Patent
active
043149871
ABSTRACT:
A process for differential diagnosis of various rheumatological and arthritic diseases, all of which may yield similar antinuclear antibody test results. The process comprises a continuous sequence of tests on a single serum specimen to minimize and eliminate variations, thus providing accurate results. The process involves drawing a serum from a patient and first performing an antinuclear antibody test which is evaluated. If the evaluation is positive, then the particular type of positive indication is interpreted. If the interpretation reveals peripheral or speckled immunofluorescence, then a diagnosis of active Systemic Lupus Erythematosus (SLE), or mixed connective tissue disease (MCTD) are suggested, and automatically additional confirming tests will be performed as part of the process. These tests are the anti-DNA (Deoxyribonucleic Acid), the anti-ENA (extractable nuclear antigen). The test for the complement component C3 and a muscle disease test, called a creatine phosphokinase (CPK) which is a test for an enzyme contained in skeletal muscle. The results are compiled and reported in addition to reporting the degree of positivity by titer, which is the strength of a solution or the concentration of the antinuclear antibodies determined by a series of titrations or dilutions.
REFERENCES:
patent: 3897212 (1975-07-01), Leon et al.
Metzger Allan L.
Morris Robert I.
Weiss Arnold S.
Cislo Donald M.
Kyle Deborah L.
Nucker Christine M.
O'Reilly David
Rheumatology Diagnostics Laboratory
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