Method for diagnosing periodontal diseases with a substrate spec

Details Method for diagnosing periodontal diseases with a substrate spec Method for diagnosing periodontal diseases with a substrate spec

1989-12-29

1992-08-11

Naff, David M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 27, 435 23, 435 34, 550300, 550330, 550331, 550802, C12Q 137, C12Q 130, C12Q 104, A61K 3702

Patent

active

051378116

ABSTRACT:
A method for diagnosing contraction or progress of periodontal diseases is carried and by determining periodontopathic bacteria specific aminopeptidase activity in a specimen by using as a substrate for the enzyme. The substrate is either or both compounds of the formula:

REFERENCES:
patent: 4457866 (1984-07-01), Karges et al.
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Todo et al., Histochemical observations on . . . , vol. 11, pp. 921-930, 1966.
Abiko et al., Glycylprolyl dipeptidylaminopeptidase . . . , J. Dent. Res., vol. 64, No. 2, pp. 106-111, 1985.
Nakamura et al., Salivary Enzymes: Origin and . . . , J. of Periodontal Res., vol 18, pp. 559-569, 1983.
Zambon et al., Effect of periodontal therapy on . . . , J. of Periodontal Res., vol. 20, pp. 652-659, 1985.
Saido et al., Arylamidase Activities of oral bacteria . . . , J. Dent. Res., vol. 65, No. 11, 1335-1340, Nov. 1986.
Nakamura et al., Amino peptidase activity of . . . , J. of Periodontal Research, vol. 17, pp. 597-603, 1982.

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