Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-08-23
1998-02-24
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 795, 435 792, 436518, 436531, 436805, 436811, 536 41, 536115, 536119, 554 1, 560129, G01N 33569, G01N 3353, C07C 6900
Patent
active
057211094
ABSTRACT:
A reagent for the detection of an antibody against an acid-fast bacterial antigen comprising at least one compound selected from the group comprising mycolic acids, mycolic acid salts, mycolic acid esters and esters of fatty acids having a carbon number of 14 or more other than mycolic acid with a mono- or disaccharide, a method of detecting an antibody against an acid-fast bacterial antigen using said reagent and a method of diagnosis of acid-fast bacterial infections by said detection method are simpler in procedures and offer much higher specificity in comparison with conventional reagents and methods, enabling identification of acid-fast bacterial genera (including the genera Mycobacterium, Nocardia and Rhodococcus) and acid-fast bacterial species, and thus it is possible to make diagnoses to identify the infecting acid-fast bacterium, which leads to the quick choice of therapeutic drug for the disease.
REFERENCES:
patent: 4243663 (1981-01-01), Azuma et al.
patent: 4307229 (1981-12-01), Liav et al.
patent: 4401658 (1983-08-01), Bouchaudon et al.
patent: 4666851 (1987-05-01), Lee
patent: 4806350 (1989-02-01), Gerber
patent: 5006464 (1991-04-01), Chu et al.
patent: 5049664 (1991-09-01), Yoshinaga et al.
patent: 5344759 (1994-09-01), Laszlo et al.
Kaneda et al, "Granuloma Formation & Hemopiesis Induced by Carbon 36-48-Mycolic Acid-containing Glycolipids from Nocardia Rubra", Infect. Immun., 54 (3), 1986, pp. 869-875.
Kato, 1972. Antibody Formation to Trehalose-6-6'-dimycolate (Cord Factor) of Mycobacterium tuberculosis. Infect. Immun. 5: 203-212.
Reggiardo et al, 1980. Elisa Tests for Antibodies Against Mycobacterial Glycolipids, J Immunol. Meth 34: 55-60.
Reggiardo et al, 1981. Comparison of Enzyme-Linked Immunosorbent Assay and Hemagglutination Test Using Mycobacterial Glycolipids, J Clin Microbiol 13: 1007-9.
Smolarsky, 1980, A Simple Radioimmunoassay to Determine Binding of Antibodies to Lipid Antigens, J. Immunol. Meth 38: 85-93.
Mehta et al, 1987. Immune Responses to Sulpholipids of Mycobacterium tuberculosis H.sub.37 R.sub.v. Indian J Med Res 86: 558-63.
Bellanti, 1971. Immunology, W. B Saunders Co., Philadelphia, pp. 99-100.
Daniel et al, 1987. The Serodiagnoses of Tuberculosis and Other Mycobacterial Diseases by Enzyme-Linked Immunosorbent Assay, Am Rev Respir Dis 135: 1137-1151.
Kato, "Antibody Formation to Trehalose-6-6'-Dimycolate (Cord Factor) of Mycobacterium tuberculosis", Infection and Immunity vol. 5, pp. 203-212 (1972).
Kato, "Immunochemical Properties of Anti-Cord Factor Antibody", Infection and Immunity, vol. 7, pp. 9 to 13, 1973.
Yano, "A study on the antibody production of glycolipid containing mycolic acid", Japanese Journal of Bacteriology, vol. 44, No. 1, p. 400 (1989).
Japanese Journal of Bacteriology, vol. 44, No. 2, 1989, pp. 533-539.
Cruaud et al., "Human IgG antibodies immunoreacting with specific sulfolipids from Mycobacterium tuberculosis", Int. J. Med. Microbiol. (Zbl. Bakt.), vol. 271/4, pp. 481-485 (1989).
Goren, "Handbook of Lipid Research," vol. 6, pp. 412, 413, 415, 416, 1990.
Reggiardo, Infection and Immunity, pp. 1369 to 1374, Dec. 1976.
Kato, Infection and Immunity, pp. 9 to 13, Jan. 1973.
Kato, Characterization of Anti-Cord factor Antibody, Symposium, pp. 23 to 26, 1973.
Runyon et al, 1980. "Mycobacterium" in Manual of Clinical Microbiology, (E.H. Lennette et al, eds.) American Society for Microbiology, Washington. pp. 150-151.
Goren, 1990. "Mycobacterial Fatty Acids Esters of Sugars and Sulfosugars", in Handbook of Lipid Research. vol. 6. (M. Kates, ed.) Plenum Press, New York. pp. 363-445.
Chan et al, 1990. Am Rev Respir Dis 142: 385-389.
Minnikin et al, 1985. J Gen Microbiol 131: 1369-1374.
Besra et al, 1992. Biochemistry 31: 9832-9837.
Kato Yoshiko
Natsuhara Yayoi
Oka Shiro
Ueno Yoshiteru
Yano Ikuya
Housel James C.
Medisa Shinyaku Inc.
Sawai Pharmaceutical Co., Ltd.
Swartz Rodney P.
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