Method for diagnosing chronic hepatitis B virus infection

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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436513, 436820, C12Q 170

Patent

active

057260117

ABSTRACT:
Human antibodies that bind to woodchuck hepatitis virus core antigen are elevated in chronic hepatitis B patients in comparison to acute hepatitis B patients. Immunoassays for detection of the level of anti-WHV core antigen antibodies is used to distinguish chronic from acute hepatitis B patients.

REFERENCES:
patent: 4271145 (1981-06-01), Wands et al.
patent: 4547368 (1985-10-01), Tabor et al.
patent: 4710463 (1987-12-01), Murray
Stannard et al., "Antigenic Cross-reactions between Woodchuck Hepatitis Virus and Human Hepatitis B Virus Shown by Immune Electron Microscopy." J. Gen. Virol. 64:957-980, 1983.

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