Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-06-02
2009-11-24
Johannsen, Diana B (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S091200, C435S091510, C536S023500, C530S350000
Reexamination Certificate
active
07622249
ABSTRACT:
The present invention relates to a method for diagnosing and/or predicting a septic syndrome, wherein:a. a biological sample from the patient is made available and biological material is extracted from the biological sampleb. at least four specific reagents which are selected from the following specific reagents are made available: reagent which is specific for the target gene IL-10, reagent which is specific for the target gene TGFβ, reagent which is specific for the target gene HMG1, reagent which is specific for the target gene T-bet, reagent which is specific for the target gene IL-1β, reagent which is specific for the target gene TNFα and reagent which is specific for the target gene GATA-3c. the expression of at least four target genes selected from: IL-10, TGFβ, HMG1, T-bet, IL-1β, TNFα and GATA-3 is determined.The present invention also relates to a kit for diagnosing and/or predicting a septic syndrome.
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Biomerieux
Johannsen Diana B
Oliff & Berridg,e PLC
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