Method for diagnosing an increased risk for thrombosis or a gene

Details Method for diagnosing an increased risk for thrombosis or a gene Method for diagnosing an increased risk for thrombosis or a gene

1997-02-21

1999-02-23

Loring, Susan A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 72, 435 792, 435 794, 435 6, 53038825, 53038885, 5303879, 530381, C12P 2104, G01N 3353, C12Q 168, C07K 1600

Patent

active

058742565

ABSTRACT:
Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.

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