Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1989-04-19
1994-05-10
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
935 78, 536 237, C12Q 168, C12N 1531
Patent
active
053106547
ABSTRACT:
Novel methods and microorganisms are provided, where novel genetic mammalian cell invasive capability is imparted to a microorganism by the introduction of an exogenous inv or ail gene. The resulting organisms are then capable of binding to mammalian cells and are transferred to the cytoplasm. Other novel genetic capabilities may be imparted to the unicellular microorganism, which may serve as a vaccine for one or more pathogens or may introduce genetic capabilities or foreign molecules into a mammalian host cell. The sequences may be used for an in vitro screen for pathogenicity.
REFERENCES:
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Falkow Stanley
Isberg Ralph R.
Miller Virginia
Mosher Mary E.
Schwartz Richard A.
The Board of Trustees of the Leland Stanford Junior University
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