Method for determining the turnover of organic material in livin

Details Method for determining the turnover of organic material in livin Method for determining the turnover of organic material in livin

1987-06-05

1989-12-26

Jaworski, Francis

Surgery

Truss

Pad

324307, A61B 504

Patent

active

048891266

ABSTRACT:
A method for determining the turnover of organic material stored in living organic tissue consists in that the deuterium content of the stored material is artificially modified from natural abundance and monitored as a function of time by measuring the CHD-signal by means of magnetic resonance spectroscopy. E.g., for determining the fat turnover in living beings, the deuterium content of the body fat may be increased by administering to the living being drinking water contaiing 10% D.sub.2 O for 28 days. Thereafter, the decrease of the deuterium content of the body fat is monitored while normal water is administered. The loss of .sup.2 H from body fat is an indication for the body fat turnover.

REFERENCES:
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Biochemistry, vol. 23, No. 3, 1984, pp. 508-514.
Journal of the Chemical Society, Chemical Communications, No. 16, 1985, pp. 1125-1127.

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