Method for determining the fibrinogen level of a blood sample

Details Method for determining the fibrinogen level of a blood sample Method for determining the fibrinogen level of a blood sample

1988-05-27

1992-10-20

Housel, James C.

Chemistry: analytical and immunological testing

Clotting or clotting factor level tests

436171, 436805, 435 4, 435 13, 73 6443, 36441309, 356 39, G01N 3386

Patent

active

051569744

ABSTRACT:
A method for determining the fibrinogen level of a patient blood plasma in an optical density based prothrombin time test. The method and apparatus utilize a novel parameter DELTA which factors out statistical inaccuracies associated with prior art test methods. The patient fibrinogen level is determined using DELTA points calculated from blood samples having known fibrinogen levels in the low, normal and high ranges. A piece wise function is then constructed around the DELTA points and the fibrinogen level of a patient blood sample is calculated using four equations pre-stored in a non-volatile memory.

REFERENCES:
patent: 3307392 (1967-03-01), Owen et al.
patent: 3458287 (1969-07-01), Gross et al.
patent: 4047890 (1977-07-01), Eichelberger et al.
patent: 4289498 (1981-07-01), Baughman et al.

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