Surgery – Diagnostic testing – Cardiovascular
Reexamination Certificate
2007-03-27
2007-03-27
Nasser, Robert L. (Department: 3735)
Surgery
Diagnostic testing
Cardiovascular
C600S505000
Reexamination Certificate
active
10444280
ABSTRACT:
In a method for determining the effectiveness of a therapy for alleviating a constriction in a blood vessel, the functioning of collateral vessels naturally formed at the constriction is analyzed. The analysis takes place by making a blood flow measurement at the vessel in which the constriction is present, or at a complementary vessel, with the patient experiencing two different stress conditions. The flow measurement can ensue by magnetic resonance or using ultrasound. Comparison of the stress-dependent blood flow to a reference is then undertaken to determine whether the collateral vessels are functioning effectively, and thus whether the treatment for alleviating the constriction is effective.
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Yang, H.T. et al., “bFGF Increases Collateral Blood Flow in Rats With Femoral Arterial Ligation,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 278: H85-H93, 2000.
Fuchs Friedrich
Kuth Rainer
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