Method for determining pyrogen content

Chemistry: analytical and immunological testing – Including sample preparation – Liberation or purification of sample or separation of...

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436 86, 436501, 436503, G01N 3300

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active

053427858

ABSTRACT:
A method for determination of a pyrogen content which comprises bringing a specimen into contact with an adsorbent composed of a nitrogen-containing heterocyclic compound bonded to a water-insoluble carrier directly or through a spacer, and after or without eluting the pyrogen adsorbed on the adsorbent, determining the content of the adsorbed pyrogen by the Limulus method.

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Kawaski, Konoshin; "Detection of Bacterial Endotoxin in Water Samples by Limulus Amebocyte Lysate Method" Bokin Bobai 17(5) 221-7, 1989.
Zimmermann, G.; Kiltz, R.; Krueger, D., "Removal of Interfering Substances with Disposable Ultrafillers in Endotoxin Determination by Means . . . Limulus Test" Drugs Made Ger. 31(3) 96-100, 1988.

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