Method for determining predisposition to severe forms of autoimm

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 536 243, 536 2433, 935 6, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104

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058306528

ABSTRACT:
The present invention provides a method for determining whether a patient has a predisposition to develop severe forms of autoimmune disease. The method involves determining whether the Fc.gamma. receptor allelic pattern of the patient corresponds most closely to known Fc.gamma. receptor allelic patterns of patients having no autoimmune disease, mild autoimmune disease, or severe autoimmune disease. The invention also encompasses methods for determining if a patient has a predisposition to infection by certain encapsulated bacteria.

REFERENCES:
patent: 5219728 (1993-06-01), Khayat et al.
Osbourne et al. J. Immunol. Methods 173:207-217 (Aug. 1, 1994).
P.A. Ory et al. Sequences of complementary DNAs that encode NAl and NAZ forms of Fc RIII on human neutrophils. J. Clin. Invest. Nov. 1989 vol. 84 p. 1688-1691.
B. Leaker and G. Cambridge "Clinical use of antineutrophil cytoplasmic antibodies" British Journal of Hospital Medicine Nov. 1993 50(9)540-8.
J.C. Jennette & R.J. Falk "Clinical and pathological classification of ANCA-associated vasculitis: What are the controversies?" 6th internation ANCA workshop Jul. 1995 In. Clincal and Exp. Immunol. 101(Supl):18-22.
Blasini et al., 1993, Clinical and Experimental Immunology, 94:423-428.
Barrett, 1983, Textbook of Immunology, Forth ed.: 277-281.
Joklik, 1984, Zinsser Microbiology, 18th ed.: 481.
Bredius et al., 1993, Journal of Immunology, 151:1463-1472.
Clark et al., 1991, European Journal of Immunology, 21:1911-1916.
Salmon et al., 1992, J. Clin. Invest., 89:1274.
Frank et al., 1979, N. Engl. J. Med., 300:518.
Fijen et al., 1993, Ann. Int. Med., 119:636.
Saiki et al., 1988, Science, 239:487.
Maxam and Gilbert, 1977, Proc. Natl. Acad. Sci. USA.
Sanger et al., 1977, Proc. Natl. Acad. Sci. USA, 74:5463.
Chomocyznski et al., 1987, Anal. Biochem., 162:156.
Gosselin et al., 1990, J. Immunol., 144;1817Chehab et al., (1987), Nature, 329:293-294.
Biasini, AM et al., 1993, Arthritis Rheum 36:S195.
Porges et al., Journal of Immunology, 153:1271-1280, 1994.
Warmerdam et al., Journal of Immunology, 147:1338-1343, 1991.

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