Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-03-13
2000-08-22
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 435 911, 435 912, 435 9121, 536 231, 536 232, 536 243, C12Q 168, G01N 3353, C12P 1934, C07H 2104
Patent
active
061070351
ABSTRACT:
A method for determining if a pig is predisposed to boar taint comprising assaying for a low molecular weight isoform of cytochrome b5 in a sample from the pig.
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Ozols, J. 1989, "Structure of cytochrom b5 and its topology in the microsomal membrane", Biochimica et Biophysica Acta, 997:121-130.
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Giordano, S.J. and Steggles, A.W. 1993. Differential expression of the MRNA's for the soluble and membrane-bound forms of rabbit cytochrome b5. Biochim. Biophys. Acta. 1172:95-100.
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Li, X.R, Giordano, S.J., Yoo, M. and Steggles, A.W. 1995. The isolation and characterization of the human cytochrome b5 gene. Biochem. Biophys. Res. Comm., vol. 209, No. 3, pp. 894-900.
Meadus, W.J., Mason, J.I. and E.J. Squires. 1993. Cytochrome P450c17 from porcine and bovine adrenal catalyses the formation of 5,16-androstadien-3.beta.-ol from pregnenolone in the presence of cytochrome b5. J. Steroid Biochem. Molec. Biol. 46(5):565-572.
Sakai, Y., Yanase, T., Takayanagi, R., Nako, R., Nishi, Y., Haji, M., and H. Nawata. 1993. High expressionof cytochrome b5 in adrenocortical adenomas from pateints with Cushings syndrome associated with high secretion of adrenal androgens. J. Clin. Endocrinol. Metab. 76:1286.
Davis Shawn
Squires E James
Steggles Alan W.
VanDerMark Petra
Horlick Kenneth R.
Siew Jeffrey
University of Guelph
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