Method for determining precorneal retention time of ophthalmic f

Details Method for determining precorneal retention time of ophthalmic f Method for determining precorneal retention time of ophthalmic f

1993-12-30

1997-06-03

Cohen, Lee S.

Surgery

Truss

Pad

128645, 128898, A61B 500, A61B 600

Patent

active

056344589

ABSTRACT:
Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescently labelled formulation to an eye, said fluorescently labelled formulation forming a thin film on the eye surface. Apparatus is provided for illuminating the eye to cause fluorescence of the fluorescently labelled formulation as the fluorescently labelled formulation thin film is eliminated from the eye by normal blinking and lacrimation; and for measuring fluorescence from the thin film as a function of time.

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