Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-o
Patent
1985-03-18
1988-05-31
Warden, Robert J.
Chemistry: analytical and immunological testing
Heterocyclic carbon compound
Hetero-o
422 61, 436 64, 436 71, 436 87, 436164, 436178, G01N 3300, G01N 3348, G01N 3122, G01N 118
Patent
active
047481285
ABSTRACT:
The amount of lipid bound sialic acid in a blood plasma or serum sample may be determined by a method which may be automated involving the following steps: diluting the sample with distilled water; mixing and then cooling the diluted sample; adding a mixture of a chlorinated lower alkyl hydrocarbon and a lower alkyl alcohol; mixing, diluting with water and then treating by mixing further and centrifuging to yield a substantially clear upper phase; recovering the upper phase and adding to it a mixture of a protein precipitating agent and adsorbing material, mixing the resulting admixture; recovering the resulting precipitate, suspending the precipitate in distilled water and determining the amount of lipid bound sialic acid present.
REFERENCES:
patent: 4115062 (1978-09-01), Morre et al.
patent: 4146603 (1979-03-01), Davidson et al.
patent: 4342567 (1982-08-01), Katopodis et al.
patent: 4457865 (1984-07-01), Miller
patent: 4493898 (1985-01-01), Sallay
Silver et al., Cancer Research, 39: 5036-5042, 1979.
Kloppel et al., Proc. Nat'l. Acad. Sci., USA, vol. 74, No. 7, pp. 3011-3013, Jul. 1977.
Dianon Systems, Inc.
Foley Shawn P.
Warden Robert J.
White John P.
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