Chemistry: analytical and immunological testing – Involving production or treatment of antibody – Monoclonal antibody
Patent
1994-07-18
1995-11-21
Scheiner, Toni R.
Chemistry: analytical and immunological testing
Involving production or treatment of antibody
Monoclonal antibody
435 71, 435965, 435971, 436518, 436536, 436540, 436822, 5303871, 5303872, 53038825, 5303889, 5303911, 5303913, G01N 3353
Patent
active
054686512
ABSTRACT:
A method is described for determining a hapten which method comprises (i) contacting the hapten with a binding partner of the hapten, whereby the hapten becomes bound to some of the binding partner, (ii) contacting the unbound binding partner with a secondary binding partner therefor, (iii) contacting the binding partner with an antibody which binds the binding partner which has bound thereto the hapten but which does not bind the binding partner which has bound thereto its secondary binding partner; and (iv) determining the amount of antibody bound to the binding partner. Kits for use in the method are also described.
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K. M. Gorman et al., Clin Chem, Fol. 37, No. 6, 1991 Antiidiotypic Antibodies as Alternative Labels in Competitive Immunoassays for Thyroxine.
Roitt, "Essential Immunology", Blackwell Scientific Publications, Oxford, England, p. 43 (1977).
Cambridge Patent Developments Limited
Scheiner Toni R.
Wolski Susan C.
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