Method for determining flush interference in measurement of chem

Details Method for determining flush interference in measurement of chem Method for determining flush interference in measurement of chem

1992-12-29

1994-04-19

Warden, Robert J.

Chemistry: analytical and immunological testing

Blood gas

128634, 128673, 356 41, 422 8212, 422 83, 436 34, 436147, 436163, G01N 2520, G01N 3348, G01N 3350, A61B 502

Patent

active

053044959

ABSTRACT:
A system (10) for in vivo measuring chemical and physical parameters of a patient's blood includes a probe (12), a sensing system (14), and flush interference warning devices (20). The system measures pH, pCO.sub.2, and temperature values, and determines a base excess value using the measured pH and pCO.sub.2. The time rate of change of the base excess value is also determined, as is the time rate of change of temperature. The warning devices are activated, indicating that the measured parameters are likely affected by the presence of flush solution flowing past the probe, when either: (a) the base excess value is less than a predefined threshold base excess; (b) the absolute value of the time rate of change of the base excess value is greater than a predefined threshold time rate of change of base excess; or, (c) the absolute value of the time rate of change of temperature is greater than a predefined threshold time rate of change of temperature.

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Burnett et al., "Tentative Standard for Definitions of Quantities and Conventions Related to Blood pH and Gas Analysis," National Committee for Clinical Laboratory Standards (NCCLS) Publication; vol. 2, No. 10, Published Aug. 1982, .COPYRGT.1982, pp. 336-350 (plus cover sheet).

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