Method for determining expression of a PI3 kinase gene

Details Method for determining expression of a PI3 kinase gene Method for determining expression of a PI3 kinase gene

1999-06-03

2008-09-09

Navarro, Mark (Department: 1645)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C424S424000, C424S185100, C424S192100, C435S004000, C435S007210, C435S091100, C435S091200, C435S091210, C435S091310, C435S091510, C435S194000, C436S501000

Reexamination Certificate

active

07422849

ABSTRACT:
This invention relates to new polypeptides which exhibit kinase activity or, more specifically, which show phosphoinositide (PI) 3-kinase activity. Such polypeptides are involved in pathways responsible for cellular growth and differentiation. An isolated polypeptide which possesses PI3-kinase activity when produced by recombinant production in insect cells is disclosed.

REFERENCES:
Carpenter et al. 1990. J. of Biol. Chem. 265(32):19704-19711.
Escobedo et al. 1991. Cell. 65:75-82.
Escobedo et al. 1991. Mol. and Cell. Bio. 11(2): 1125-1132.
Otsu et al. 1991. Cell. 65:91-104.
Skolnik et al. 1991. Cell. 65:83-90.

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