Method for determining compound interaction with E2 binding prot

Details Method for determining compound interaction with E2 binding prot Method for determining compound interaction with E2 binding prot

1996-03-06

1998-06-23

Carlson, Karen C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 793, 435 71, 435 5, 435 691, 435 697, 514 2, 536 2372, 530300, 530350, C12Q 100, C12P 2106, C07K 14025

Patent

active

057703841

ABSTRACT:
E2-BP polypeptides, nucleic acids encoding E2-BP polypeptides, and uses thereof.

REFERENCES:
patent: 5219990 (1993-06-01), Androphy et al.
patent: 5464936 (1995-11-01), Botchan et al.
Ushikai et al., "Trans activation by the full-length E2 proteins of human papillomavirus type 16 and bovine papillomavirus type 1 in vitro and in vivo: cooperation with activation domains of cellular transcription factors", J. Virology 68(10):6655-6666 (1994).
DelVecchio, A.M. et al. (1992) "Transient Replication of Human Papillomavirus DNAs" J. Virol. 66(10):5949-5958.
Thierry F. and Yaniv M. (1987) "The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV-18 regulatory region" The EMBO J 6: 3391-3397.
Yang Y-C et al. (1985) "Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1" Nature 318: 575-577.
McBride A.A. et al. (1991) "The papillomavirus E2 regulatory proteins" J. Biol. Chem. 266(26):18411-18414.
Hwang E-S et al. (1993) "Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene"J. Virol. 67(7): 3720-3729.
Giri I. and Yaniv M. (1988) "Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains" The EMBO J. 7(9): 2823-2829.
McBride A.A. et al. (1989) "E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: Transactivation is mediated by the conserved amino-terminal domain" PNAS USA 86: 510-514.
Winokur P. and McBride A.A. (1992) "Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein" The EMBO J. 11(11):4111-4118.
Adams et al., "3,400 new expressed sequence tags identify diversity of transcripts in human brain", Nature Genetics 4;256-267 (1993).
Androphy et al., "Isolation of human cDNAs that interact with the papillomavirus E2 transcription protein", J Investigative Dermatology 100(4): 526 (1993).
Breiding et al., "Isolation of a novel human gene that interacts with the papillomavirus E2 transcription/replication protein", J. Investigative Dermatology 102(4):452 (1994).

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