Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1986-05-22
1988-06-21
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436518, 436531, 436825, 436826, 436828, G01N 3353
Patent
active
047525711
ABSTRACT:
Method and means in/for the immunoassay determination of (I) a bacterial polypeptide capable of binding to the Fc protion of an immunoglobulin and/or (II) the high affinity antibody to said polypeptide. The characteristic feature of the method resides in using an antibody directed against the polypeptide and having antibody activity under conditions such that the immunoglobulin potentially binding to the polypeptide will substantially not bind to the polypeptide, and carrying out the immune reaction between the antibody preparation and the corresponding polypeptide epitope under such conditions.
REFERENCES:
patent: 3966868 (1976-06-01), Sjoquist et al.
patent: 3995018 (1976-11-01), Sjoquist et al.
patent: 4409330 (1983-10-01), Pollard, Jr.
patent: 4469796 (1984-09-01), Axen et al.
patent: 4471058 (1984-09-01), Smith et al.
patent: 4590168 (1986-05-01), Sytkowski et al.
patent: 4617266 (1986-10-01), Fahnestock
Erntell et al., "Alternative Non-Immune F(ab').sub.2 -Medicated Immunoglobulin Binding to Group C and G Streptococei" Scand. J. Immunol. 17:201-209 (1983).
Inganas et al., "Further Characterization of the Alternative Protein-A, Interaction of Immunoglobulins: Demonstration of an Fc-binding Fragment of Protein A Expressing the Alternative Reactivity" Scan. J. Immunol. 14:379-388 (1981).
Kinet, "Ex vivo Perfusion of Plasma Over Protein A Columns in Human Mammary Adenocarcinoma Evidence for a Protein A Leaking by Radio Immunoassay" Eur. J. Clin. Invest. 16:43-49 (1986).
Martin, "Chromatographic Fractionation of Rhesus Monkey (Macaca Mulatta) IgG Subclasses Using DEAE Cellulose and Protein A-Sepharose, J. Immol. Meth., 50 (1982) 319-329.
Langone et al., "Radioimmunoassays for Protein A of Staphylococcus aureus", J. Immunol. Meth., 63 (1983) 145-157.
Dertzbaugh et al., "An Enzyme Immunoassay for the Detection of Staphylococcal Protein A in Affinity-Purified Products", J. Immunol. Meth. 83 (1985) 169-177.
Juarez-Salinas et al., "Binding of IgG to Protein A", Chem. No., 105 (1986) #189332k.
Berglund Asta
Inganas Mats W.
Nucker Christine M.
Pharmacia AB
Philpitt Fred
LandOfFree
Method for determining certain bacterial polypeptides and antibo does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for determining certain bacterial polypeptides and antibo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for determining certain bacterial polypeptides and antibo will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-929702