Method for determining cell cycle position

Details Method for determining cell cycle position Method for determining cell cycle position

2007-06-26

2007-06-26

Guzo, David (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C435S325000, C435S366000, C435S367000, C435S455000, C435S004000, C435S069100, C514S002600, C536S023100, C536S023400, C530S350000

Reexamination Certificate

active

10491762

ABSTRACT:
The invention provides a novel, non-destructive and dynamic process for determining the cell cycle position of living cells. The invention also provides DNA constructs, and cell lines containing such constructs, that exhibit activation and deactivation of a detectable reporter molecule in a cell cycle specific manner. The invention thus allows greater precision in determining cell cycle phase status than existing techniques and further provides a method for continuous monitoring of cell cycle progression in individual cells.

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