Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Chemical analysis
Reexamination Certificate
2008-02-29
2010-10-12
Charioui, Mohamed (Department: 2857)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Chemical analysis
C702S027000, C702S028000, C422S063000, C422S070000, C422S105000, C210S635000, C210S656000
Reexamination Certificate
active
07813882
ABSTRACT:
A new method is presented for measuring the molecular properties of an unfractionated solution of macromolecules. Sample aliquots spanning a range of concentrations are injected sequentially into a stream of solution and flow towards the detectors. Each aliquot produces, thereby, an effective “peak” whose elements correspond to different concentrations of the diluted aliquot. The weight averaged molar mass, the mean square radius, and the second virial coefficient of the macromolecules in solution are derived from an analysis of the angular and concentration dependence of the scattering signals throughout the corresponding peaks. In contrast to earlier on-line methods, better accuracy is achieved, while using a smaller quantity of sample. A similar method for determining cross virial coefficients between two distinct species of macromolecules is also presented.
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Some Daniel I.
Trainoff Steven P.
Charioui Mohamed
Desta Elias
Villalpando David N.
Wyatt Philip J.
Wyatt Technology Corporation
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