Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-10-19
2010-10-26
Saoud, Christine J (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C436S501000
Reexamination Certificate
active
07820396
ABSTRACT:
It is an object of the present invention to find substances that can be used as disease markers for atopic dermatitis and the present invention provides a method for determining atopic dermatitis, including measurement of the expression of specific proteins and/or their genes in skin cells and/or skin tissues, wherein the specific proteins change their expression with inflammation caused by atopic dermatitis or change their expression according to the degree of predisposition to atopic dermatitis. The present invention also provides a kit for determining the degree of inflammation of atopic dermatitis or risk of developing atopic dermatitis, as well as a method for determining substances effective in the treatment and/or prevention of atopic dermatitis.
REFERENCES:
patent: 2005-110602 (2005-04-01), None
patent: WO 01/65259 (2001-09-01), None
Bowcock (Human Molecular Genetics (2001) vol. 10, p. 1793).
K. Mitsuishi, et al, “The squamous cell carcinoma antigens as relevant biomerkers of atopic dermatitis,” Clin Exp Allergy 2005, 35, pp. 1327-1333.
M. Toyoda, et al., “Clinical and Laboratory Investigations Nerve Growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis,” British Journal of Dermatology 2002, 147, pp. 71-79.
I. Angelova-Fischer, et al., “Significance of interleukin-16, macrophage-derived chemokine, eosinophil cationic protein and soluble E-selectin in reflecting disease activity of atopic dermatitis—from laboratory parameters to clinical scores,” British Journal of Dermatology 2006, 154, pp. 1112-1117.
Yong-Doo Park, et al., “Towards a proteomic analysis of atopic dermatitis: A two-dimensional-polyacrylamide gel electrophoresis/mass spectrometric analysis of cultured patient-derived fibroblasts,” Proteomics 2004, 4, pp. 3446-3455.
Yong-Doo Park, et al., “Two-dimensional electrophoretic profiling of atopic dermatitis in primary cultured keratinocytes from patients,” Protemics 2006, 6, pp. 1362-1370.
Satoshi Miyata, “Finding Proteins Relating to Prevention of Skin Aging,” New Material Exploration Group, Central Research Laboratory, Fancl Corporation, pp. 41- 45.
Momoko Takakura, et al., “Differences in Cytokine Production between NC/Nga Mice with and without Atopic-Dermatitis-like Lesion,” Nitikawa Kaishi, 2004, vol. 114, No. 2, pp. 1881-1887.
Aihara Michiko
Ikezawa Zenro
Iwamatsu Akihiro
Miyata Satoshi
Miyazaki Kaoru
Aihara Michiko
Fancl Corporation
Ikezawa Zentro
Knobbe Martens Olson & Bear LLP
Miyazki Kaoru
LandOfFree
Method for determining atopic dermatitis using protein marker does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for determining atopic dermatitis using protein marker, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for determining atopic dermatitis using protein marker will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4195193