Image analysis – Applications – Biomedical applications
Patent
1997-11-28
2000-06-13
Chang, Jon
Image analysis
Applications
Biomedical applications
378 37, 382248, G06K 900
Patent
active
060758783
ABSTRACT:
A computer-aided diagnosis (CAD) method for detection of clustered microcalcifications in digital mammograms based on an image reconstruction using a substantially optimally weighted wavelet transform. Weights at individual scales of the wavelet transform are optimized based on a supervised learning method. In the learning method, an error function represents a difference between a desired output and a reconstructed image obtained from weighted wavelet coefficients of the wavelet transform for a given mammogram. The error function is then minimized by modifying the weights by means of a conjugate gradient algorithm. Performance of the optimally weighted wavelets was evaluated by means of receiver-operating characteristic (ROC) analysis which indicated that the present invention outperformed both a difference-image technique and partial reconstruction method currently used in CAD methods.
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Doi Kunio
Nishikawa Robert M.
Yoshida Hiroyuki
Zhang Wei
ARCH Development Corporation
Chang Jon
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