Measuring and testing – With fluid pressure – Porosity or permeability
Reexamination Certificate
2007-10-16
2007-10-16
Kim, John (Department: 1723)
Measuring and testing
With fluid pressure
Porosity or permeability
C201S045000, C201S045000, C201S045000, C201S045000
Reexamination Certificate
active
11503791
ABSTRACT:
The method for determining an effective Peclet number for a membrane adsorber device includes the steps of (a) equilibrating the membrane adsorber device with an equilibration buffer at a known pH and conductivity; (b) challenging the membrane with a known concentration of a specific solute in said equilibration buffer; (c) monitoring the breakthrough of the solute downstream of the membrane as a function of a value selected from the group consisting of time, challenge volume and other suitable variable related to total quantity of material challenged to membrane adsorber device; (d) analyzing the solute breakthrough curve to determine pertinent flow characteristics of said membrane adsorber device by calculating the sharpness of the breakthrough curve of the membrane adsorber device and (e) comparing the results calculated in step (d) to results from known integral devices to determine the effective Peclet number.
REFERENCES:
patent: 2788901 (1957-04-01), Boeddinghause et al.
patent: 3158532 (1964-11-01), Pall et al.
patent: 4007113 (1977-02-01), Ostreicher
patent: 4007114 (1977-02-01), Ostreicher
patent: 4305782 (1981-12-01), Ostreicher et al.
patent: 4340482 (1982-07-01), Sternberg
patent: 4347208 (1982-08-01), Southall
patent: 4618533 (1986-10-01), Steuck
patent: 4895806 (1990-01-01), Le et al.
patent: 4923901 (1990-05-01), Koester et al.
patent: 4944879 (1990-07-01), Steuck
patent: 5019270 (1991-05-01), Afeyan et al.
patent: 5085749 (1992-02-01), Grimshaw et al.
patent: 5085784 (1992-02-01), Ostreicher
patent: 5128037 (1992-07-01), Pearl et al.
patent: 5137633 (1992-08-01), Wang
patent: 5147542 (1992-09-01), Proulx
patent: 5176828 (1993-01-01), Proulx
patent: 5282964 (1994-02-01), Young et al.
patent: 5348982 (1994-09-01), Herbolzheimer et al.
patent: 5433847 (1995-07-01), Rice
patent: 5531899 (1996-07-01), Yen et al.
patent: 5547760 (1996-08-01), Tarbet et al.
patent: 5618433 (1997-04-01), Tarbet et al.
patent: 5629084 (1997-05-01), Moya
patent: 5679249 (1997-10-01), Fendya et al.
patent: 5760183 (1998-06-01), Dazey et al.
patent: 5814372 (1998-09-01), Moya
patent: 5824217 (1998-10-01), Pearl et al.
patent: 5922200 (1999-07-01), Pearl et al.
patent: 5928588 (1999-07-01), Chen et al.
patent: 5951972 (1999-09-01), Daley et al.
patent: 5980987 (1999-11-01), Tarbet et al.
patent: 6365395 (2002-04-01), Antoniou
patent: 563687 (1944-08-01), None
patent: 599909 (1948-03-01), None
patent: 00/09239 (2000-02-01), None
patent: 01/83077 (2001-11-01), None
The International Search Report dated May 23, 2003 (PCT/US02/32504).
The International Search Report dated Jun. 2, 2003 (PCT/US02/34960).
Tejeda A et al.: “Optimal design of affinity membrane chromatographic columns” Journal of Chromatography A, Elsevier Science, NL., vol. 830, No. 2, Jan. 15, 1999, pp. 293-300, p. 294, p. 299.
Roper D K et al.: “Separation of biomolecules using adsorptive membranes” Journal of Chromatography A, Elsevier Science, NL., vol. 702, No. 1/2, May 19, 1995, pp. 3-26, abstract.
Lapidus, et al., “Mathematics of Adsorption I Beds. IV. The Effect of Longitudinal Diffusion in Ion Exchange and Chromatographic columns”, J. Phys. Chem. 56, 984 (1952).
ACS Publications; Xianfang Zeng; October 29, 1999; “Membrane Chromatography: Preparation and Applications to Protein Separation” Abstract.
Kim John
Millipore Corporation
Nields & Lemack
LandOfFree
Method for determining an effective peclet number for a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for determining an effective peclet number for a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for determining an effective peclet number for a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3872480