Method for determination of inflammatory bowel disease

Details Method for determination of inflammatory bowel disease Method for determination of inflammatory bowel disease

2007-05-18

2011-10-25

Liu, Sue (Department: 1653)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

Reexamination Certificate

active

08043832

ABSTRACT:
The instant invention provides a method for the differential diagnosis of inflammatory bowel disease which comprises,determining the relative ratio of G0 oligosaccharide represented by formula (I):to G2 oligosaccharide represented by formula (II):wherein G represents galactose, M represents mannose, GN represents N-acetylglucosamine and F represents fucose in serum IgG oligosaccharide fraction obtained from a patient with inflammatory bowel disease or a patient with suspicion of inflammatory bowel disease, anddiscriminating inflammatory bowel disease based on the obtained ratio.

REFERENCES:
patent: 6777197 (2004-08-01), Shimoyama et al.
patent: 2005/0074818 (2005-04-01), Bergmann et al.
patent: 0 698 793 (1996-02-01), None
patent: 0 756 173 (1997-01-01), None
patent: 07-209301 (1995-08-01), None
patent: 08-82623 (1996-03-01), None
patent: 08-220099 (1996-08-01), None
patent: 2005-504321 (2005-02-01), None
patent: WO 99/34218 (1999-07-01), None
patent: WO 03/029824 (2003-04-01), None
patent: WO 2005/054853 (2005-06-01), None
Bond et al. “A detailed lectin analysis of IgG glycosylation, demonstrating disease specific changes in terminal galactose and N-acetylglucosamine”, J of Autoimmunity, 1997, 10:77-85.
Alavi et al. “The pivotal nature of sugars in normal physiology and disease”, WMW, 2006, 156(1-2):19-33.
Kuroda, et al., “Structural Studies on IgG Oligosaccharides of Patients with Primary Sjögren's Syndrome”, Glycoconjugate Journal, vol. 19, No. 1, Jan. 2002, pp. 23-31.
Masuda, et al., “Pairing of Oligosaccharides in the Fc Region of Immunoglobulin G”, FEBS Letters, vol. 473, No. 3, May 19, 2000, pp. 349-357.
Parekh et al., “A Comparative Analysis of Disease-Associated Changes in the Galactosylation of Serum IgG”, Journal of Autoimmunity, vol. 2, No. 2, Apr. 1, 1989, pp. 101-114.
Tsuchiya, et al., “Detection of Glycosylation Abnormality in Rheumatoid IgG using N-Acetylglucosamine-Specific Psathyrella Velutina Lectin” The Journal of Immunology, vol. 151, No. 2, Jul. 15, 1993, pp. 1137-1146.
Supplementary European Search Report for PCT/JP2007/060257 Dated Nov. 3, 2009.
Written Opinion of the International Searching Authority, Application No. PCT/JP2007/060257, mailed Jul. 24, 2007 (English Translation).
Thomas W. Rademacher et al., “The Role of IgG Glycoforms in the Pathogenesis of Rheumatoid Arthritis”, Springer Seminar Immunopathology, 1988, pp. 231-249, vol. 10.
R Dubé et al., “Agalactosy IgG in Inflammatory bowel disease: Correlation with C-Reactive Protein”, Gut, 1990, pp. 431-434, vol. 31.
Mae F. Go et al., “Deficient Galactosylation of Serum IgG in Inflammatory Bowl Disease: Correlation with Disease Activity”, J. Clin Gastroenterol, 1994, pp. 86-87, vol. 18(1).
Takara Bio Online Catalogue, Method for Analyzing Human IgG Oligosaccharides using Palstation, http://bio.takara.co.jp/catalog/catalog—d.asp?C—ID=C0730, Mar. 15, 2006, pp. 1-6 (with full English Translation).
Picolumi® CA RF, “A Diagnosing kit for the Determination Serum Anti-Agalactosy IgG Anitbodies”, pp. 1-20 (with full English translation). Feb. 2005.

Affiliated with

Also associated with

Rating

Method for determination of inflammatory bowel disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for determination of inflammatory bowel disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for determination of inflammatory bowel disease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4290849