Method for detection of peritoneal inflammation or infection

Details Method for detection of peritoneal inflammation or infection Method for detection of peritoneal inflammation or infection

1984-10-05

1987-03-31

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 18, 435 21, 435 28, C12Q 300

Patent

active

046542981

ABSTRACT:
Peritoneal inflammation or infection can be detected in a patient by assaying a peritoneal lavage sample from the patient for lysosomal enzymes. This is done by combining the lavage sample with a leukocyte lysing agent and a chromogenic or fluorogenic enzyme substrate specific for lysosomal enzymes. The lysosomal enzymes can then be measured, and the inflammation or infection detected, by measuring the color or fluorescence developed in the sample by action of the enzymes on the substrate.

REFERENCES:
Lucisano et al-Chem. Abst., vol. 100 (1984), p. 172,883q.
Ring-Chem. Abst, vol. 100 (1984) p. 215,366t.

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