Method for detection of growth differentiation factor-12 polypep

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 721, 424 111, 424 149, 424 169, 424 91, 4241301, 4241391, 4241451, G01N 3353, A61K 5110

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active

061300500

ABSTRACT:
Growth differentiation factor-12 (GDF-12) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-12 polypeptide and polynucleotide sequences.

REFERENCES:
Expression of growth/differentiation factor 1 in the nervous system: Conservation of a bicistronic structure, Se-Jin Lee, Proc. Natl. Acad. Sci. USA., 88:4250-4254, May 1991.
GDF-3 and GDF-9: Two New Members of the Transforming Growth Factor-B Superfamily Containing a Novel Pattern of Cysteines*--McPherron, et al., The journal of Biological Chemistry, #5, 268:3444-3449, Feb. 15, 1993.
Identification of Novel Member (GDF-1) of the Transforming Growth Factor-B Superfamily Se-Jin Lee, Mol. ENDO, No. 7, 4:1034-1039, 1990.

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