Method for detection of an analyte using acridinium ester and li

Details Method for detection of an analyte using acridinium ester and li Method for detection of an analyte using acridinium ester and li

1994-10-19

1997-01-21

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

546102, 514297, C12Q 168

Patent

active

055958753

ABSTRACT:
A method for the detection of an analyte in a fluid sample using liposomes encapsulating acridinium esters (lumisomes). Hydrophilic polysubstituted aryl acridinium esters are useful as chemiluminescent markers and can be encapsulated within liposome vesicles without significant leakage of the esters from the vesicles. The lumisomes can be coupled to molecules with biological activity, such as antigens, antibodies, and nucleic acids, and used in luminescent assays.

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