Method for detecting the .gamma.,.delta. T cell receptor

Details Method for detecting the .gamma.,.delta. T cell receptor Method for detecting the .gamma.,.delta. T cell receptor

1986-07-03

1994-02-15

Hill, Jr., Robert J.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436548, 436506, 435 71, 435 724, 4352402, 4351722, 53038822, 53038875, 5303896, 935101, G01N 33566

Patent

active

052866530

ABSTRACT:
The present invention provides purified polypeptides which comprise at least a portion of a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide or a .gamma.,.delta. T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.

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