Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2003-11-07
2010-12-07
Nickol, Gary B. (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S007700, C435S040510
Reexamination Certificate
active
07846672
ABSTRACT:
The present invention identifies autoantibodies to folate receptors. Methods to identify these autoantibodies to the human folate receptors are also provided. The present invention also contemplates diagnostic methods and test kits to be used in a clinical setting for identifying a subject at risk of folate-sensitive abnormalities or disorders as observed in neural tube defect complicated pregnancies. In addition, infertility, spontaneous abortion, male sterility, unsuccessful in vitro fertilization, neurologic disorders and impaired folate absorption may also be associated with these autoantibodies to folate receptors.
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da Costa Maria
Quadros Edward V.
Rothenberg Sheldon P.
Sequeira Jeffrey
Nickol Gary B.
Scully , Scott, Murphy & Presser, P.C.
Stoica Elly-Gerald
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