Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Reexamination Certificate
2011-04-26
2011-04-26
Yu, Melanie J (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
C436S518000, C436S524000, C436S525000, C436S807000, C435S283100, C435S287100, C435S287200
Reexamination Certificate
active
07932100
ABSTRACT:
The present invention provides a method for detecting a target substance by detecting the presence or concentration of a target substance in a sample solution by bringing the sample solution into contact with a detecting element including a detecting part and a non-detecting part and detecting the presence or number of a magnetic label (magnetic marker) present in the vicinity of the surface of the detecting part and provides a target-substance detection kit. The surface potential ψ1of the magnetic label in the sample solution, the surface potential ψ2of the detecting parts and the surface potential ψ3of the non-detecting part satisfy any one of the following relationships i) to iv):i) ψ1ψ3>0 and ψ2=0,ii) ψ1ψ2<0 and ψ3=0,iii) ψ1ψ2<0, ψ2ψ3>0, and |ψ2|>|ψ3|, andiv) ψ1ψ2<0 and ψ2ψ3<0; and the target substance borne by the magnetic label is captured by a primary capturing body borne by the detecting part, or the target substance captured by a primary capturing body borne by the detecting part is captured by a secondary capturing body borne by the magnetic label.
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Ikeda Takashi
Imamura Takeshi
Minami Masato
Nakahama Kazumichi
Ogawa Miki
Canon Kabushiki Kaisha
Fitzpatrick ,Cella, Harper & Scinto
Yu Melanie J
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