Method for detecting prostate cancer using a reagent which binds

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 436 64, 436813, G01N 33574, G01N 3353

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active

058244905

ABSTRACT:
Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. Also provided is an in vitro method for detecting prostate cancer in a sample employing a reagent that reacts with the NMP designated PC-1 (prostate cancer-1).

REFERENCES:
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Cupo, J F (1991) J. Chromatog. 569:389-406.
Getzenberg & Coffey (1990). Molec. Endocr. 4:1336-42.
Getzenberg et al. (1991) Biochem Biophys Res Comm 179:340-44.
Getzenberg et al. (1991) Cancer Res. 51:6514-20.
Partin & Coffey (1994) Rec Prog Horm Res 49:293-331.

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