Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-12-05
2006-12-05
Gabel, Gailene R. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007200, C435S007920, C435S372000, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C435S063000
Reexamination Certificate
active
07144710
ABSTRACT:
Methods for detecting the inflammatory biomarkers molecule CD 163 in biological samples are provided. Also provided are methods for monitoring the course of an inflammatory process or condition in a patient and compositions and methods for preventing and treating inflammation and inflammatory processes.
REFERENCES:
Coligan et al. (Current Protocols in Immunology, Greene Publishing Associates and Wiley-Interscience, New York, 1991., pp. 2.1.1-2.1.3. 2.1.9-2.1.11, and 2.1.17-2.1.22).
Droste et al., Shedding of CD163, a Novel Regulatory Mechanism for a Member of the Scavenger Receptor Cysteine-Rich Family, Biochemical and Biophysical Research Communications 23: 110-113 (1999).
Blaschitz et al., “Antibody Reaction Patterns in First Trimester Placenta:Implications for Trophoblast isolation and Purity Screening”, Placenta 2000 21:733-741.
Hintz et al., “Glucorticoids and LPS Synergistically Increase Expression of CD163 on Cultured Human Monocytes”, FASEB J. 2000 14 (6) :Supp. (S) , A1143, Abstract No. 148.25.
Högger et al., “Identification of the Integral Membrane Protein RM3/1 on Human Monocytes as a Glucocorticoid-Inducible Member of the Scavenger Receptor Cysteine-Rich Family (CD163)1”, J. Immunology 1998 161 (4) :1883-1890.
Van Den Heuvel et al., “Regulation of CD163 on Human Macrophages:Cross-linking of CD13 Induces Signaling and Activation”, J. Leukocyte Biol. 1999 66(5) :858-866.
Sulahian et al., “Human Monocytes Express CD163, Which is Upregulated by IL-10 and Identical To p. 155”, Cytokine 2000 12(9) :1312-1321.
Droste et al., “Shedding of CD163, a Novel Regulatory Mechanism for a Member of the Scavenger Receptor Cysteine-Rich Family”, Biochemical and Biophysical Research Communications 1999 256:110-113 XP-002296648.
Ritter et al., “The Scavenger Receptor CD163 :Regulation, Promoter Structure and Genomic Organization”, Pathobilogy 1999 67:257-261 XP009036479.
Sulahian et al., “Development of an ELISA to measure soluble CD163 in biological fluids”, Journal of Immunological Methods 2001 252:25-31 XP-002296647.
Goulding Nicholas J.
Guyre Paul M.
Morganelli Peter M.
Gabel Gailene R.
Licata & Tyrrell P.C.
Trustees of Dartmouth College
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