Chemistry: physical processes – Physical processes – Crystallization
Patent
1980-02-21
1982-03-16
Marantz, Sidney
Chemistry: physical processes
Physical processes
Crystallization
23915, 25217422, 252551, 422 73, 424 11, 424 12, G01N 3354, G01N 3380
Patent
active
043198821
ABSTRACT:
A biochemical agent for facilitating detection of immunological agglutination reactions in liquid suspensions, in particular red blood cell suspensions. The biochemical agent includes from about 0.1 to about 1 g/l of a protein-compatible, water-soluble, non-ionic surface-active polyoxyalkylene ether or ester and from about 0.1 to about 1.0 g/l of a protein compatible water-soluble anionic detergent dissolved in a buffered isotonic aqueous saline solution. When added to an agglutination reaction mixture, this biochemical agent increases the sensitivity of the agglutination reaction and promotes fast settling out of agglutinated matter from the reaction mixture, whilst non-agglutinated matter is maintained in suspension and can easily be detected therein visually by the naked eye or nephlometrically. Also, a device for automated detection of agglutination reactions in liquid suspensions. The device comprises a loading unit for receiving conventional test tube carriers carrying test tubes with the liquid suspension transport means for carrying the test tube carrier from the loading unit to two dispensing units for dispensing reagents into the test tubes, a reacting unit wherein reaction is allowed to complete, a reading unit wherein nonagglutinated suspended matter in the test tubes is detected by means of a nephlometer and finally to an unloading unit. The biochemical agent and the device for detecting immunological agglutination are particularly useful in methods for blood grouping.
REFERENCES:
patent: 3334018 (1967-08-01), Smythe
patent: 3432268 (1969-03-01), Unger
patent: 3624223 (1971-11-01), Smythe
patent: 4000121 (1976-12-01), Garcia
patent: 4104031 (1978-08-01), Robuchon-Merovak
patent: 4130395 (1978-12-01), Chryssanthou
patent: 4148869 (1979-04-01), Deaton
patent: 4184848 (1980-01-01), Batz
patent: 4282001 (1981-08-01), Klose
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