Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-01-19
1996-05-07
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 29, C12Q 102, G01N 3353
Patent
active
055145566
ABSTRACT:
A sensitive and accurate tissue culture system and kit fop detecting subtle changes in immune function is provided. The system is based on the comparison of IL-2 production by T helper cells in response to recall antigens including influenza A virus, tatanus toxoid, alloantigens, mouse xenogeneic antigens and the like or combinations thereof. Different stages of immune dysfunction can be differentiated and organ graft rejection can be predicted by the method of the present invention.
REFERENCES:
patent: 5344755 (1994-09-01), Shearer et al.
W. J. Herbert et al, Dictionary of Immunology-3rd Ed., Blackwell Scientific Publications, 1985, p. 114.
C. S. Via et al, Journ. Immunol., 144, 2524-2528, 1990.
Clerici Mario
Shearer Gene M.
Via Charles S.
Saunders David
The United States of America as represented by The Department of
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